Investigation of factors influencing the separation of diastereomers of phosphorothioated oligonucleotides

This study presents a systematic investigation of factors influencing the chromatographic separation of diastereomers of phosphorothioated pentameric oligonucleotides as model solutes. Separation was carried out under ion-pairing conditions using an XBridge C(18) column. For oligonucleotides with a...

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Detalles Bibliográficos
Autores principales: Enmark, Martin, Rova, Maria, Samuelsson, Jörgen, Örnskov, Eivor, Schweikart, Fritz, Fornstedt, Torgny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543027/
https://www.ncbi.nlm.nih.gov/pubmed/31020370
http://dx.doi.org/10.1007/s00216-019-01813-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543027/
https://www.ncbi.nlm.nih.gov/pubmed/31020370
http://dx.doi.org/10.1007/s00216-019-01813-2

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