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Purified human anti-Tn and anti-T antibodies specifically recognize carcinoma tissues

Described in several epithelial cancer cells, Tn- (GalNAcα1-O-Ser/Thr) and T- (Galβ3GalNAcα1-O-Ser/Thr) antigens are examples of tumor-associated antigens. Increased expression of Tn- and T-antigens is associated with tumor invasion and metastasis, and patients with high concentration of anti-Tn and...

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Detalles Bibliográficos
Autores principales: Zlocowski, Natacha, Grupe, Veronica, Garay, Yohana C., Nores, Gustavo A., Lardone, Ricardo D., Irazoqui, Fernando J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543037/
https://www.ncbi.nlm.nih.gov/pubmed/31147593
http://dx.doi.org/10.1038/s41598-019-44601-9