Structural and biochemical characterization of Rv0187, an O-methyltransferase from Mycobacterium tuberculosis

Catechol O-methyltransferase (COMT) is widely distributed in nature and installs a methyl group onto one of the vicinal hydroxyl groups of a catechol derivative. Enzymes belonging to this family require two cofactors for methyl transfer: S-adenosyl-l-methionine as a methyl donor and a divalent metal...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Sanghyun, Kang, Jihoon, Kim, Jungwook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543040/
https://www.ncbi.nlm.nih.gov/pubmed/31147608
http://dx.doi.org/10.1038/s41598-019-44592-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543040/
https://www.ncbi.nlm.nih.gov/pubmed/31147608
http://dx.doi.org/10.1038/s41598-019-44592-7

Ejemplares similares