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Structural and biochemical characterization of Rv0187, an O-methyltransferase from Mycobacterium tuberculosis
Catechol O-methyltransferase (COMT) is widely distributed in nature and installs a methyl group onto one of the vicinal hydroxyl groups of a catechol derivative. Enzymes belonging to this family require two cofactors for methyl transfer: S-adenosyl-l-methionine as a methyl donor and a divalent metal...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543040/ https://www.ncbi.nlm.nih.gov/pubmed/31147608 http://dx.doi.org/10.1038/s41598-019-44592-7 |