Bioengineered miR-27b-3p and miR-328-3p modulate drug metabolism and disposition via the regulation of target ADME gene expression

Drug-metabolizing enzymes, transporters, and nuclear receptors are essential for the absorption, distribution, metabolism, and excretion (ADME) of drugs and xenobiotics. MicroRNAs participate in the regulation of ADME gene expression via imperfect complementary Watson—Crick base pairings with target...

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Detalles Bibliográficos
Autores principales: Li, Xin, Tian, Ye, Tu, Mei-Juan, Ho, Pui Yan, Batra, Neelu, Yu, Ai-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Short communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543075/
https://www.ncbi.nlm.nih.gov/pubmed/31193825
http://dx.doi.org/10.1016/j.apsb.2018.12.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543075/
https://www.ncbi.nlm.nih.gov/pubmed/31193825
http://dx.doi.org/10.1016/j.apsb.2018.12.002

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