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Develop a 3D neurological disease model of human cortical glutamatergic neurons using micropillar-based scaffolds

Establishing an effective three-dimensional (3D) in vitro culture system to better model human neurological diseases is desirable, since the human brain is a 3D structure. Here, we demonstrated the development of a polydimethylsiloxane (PDMS) pillar-based 3D scaffold that mimicked the 3D microenviro...

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Detalles Bibliográficos
Autores principales: Chen, Cheng, Dong, Xin, Fang, Kai-Heng, Yuan, Fang, Hu, Yao, Xu, Min, Huang, Yu, Zhang, Xixiang, Fang, Danjun, Liu, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543078/
https://www.ncbi.nlm.nih.gov/pubmed/31193866
http://dx.doi.org/10.1016/j.apsb.2019.03.004