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Develop a 3D neurological disease model of human cortical glutamatergic neurons using micropillar-based scaffolds
Establishing an effective three-dimensional (3D) in vitro culture system to better model human neurological diseases is desirable, since the human brain is a 3D structure. Here, we demonstrated the development of a polydimethylsiloxane (PDMS) pillar-based 3D scaffold that mimicked the 3D microenviro...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543078/ https://www.ncbi.nlm.nih.gov/pubmed/31193866 http://dx.doi.org/10.1016/j.apsb.2019.03.004 |