Identification and quantification of sites of nitration and oxidation in the key matrix protein laminin and the structural consequences of these modifications

Laminin is a major protein of the basement membrane (BM), a specialized extracellular matrix (ECM) of the artery wall. The potent oxidizing and nitrating agent peroxynitrous acid (ONOOH) is formed at sites of inflammation, and data implicate ONOOH in ECM damage and cardiovascular disease. Co-localiz...

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Detalles Bibliográficos
Autores principales: Lorentzen, Lasse G., Chuang, Christine Y., Rogowska-Wrzesinska, Adelina, Davies, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543125/
https://www.ncbi.nlm.nih.gov/pubmed/31154162
http://dx.doi.org/10.1016/j.redox.2019.101226

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543125/
https://www.ncbi.nlm.nih.gov/pubmed/31154162
http://dx.doi.org/10.1016/j.redox.2019.101226

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