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Identification and quantification of sites of nitration and oxidation in the key matrix protein laminin and the structural consequences of these modifications
Laminin is a major protein of the basement membrane (BM), a specialized extracellular matrix (ECM) of the artery wall. The potent oxidizing and nitrating agent peroxynitrous acid (ONOOH) is formed at sites of inflammation, and data implicate ONOOH in ECM damage and cardiovascular disease. Co-localiz...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543125/ https://www.ncbi.nlm.nih.gov/pubmed/31154162 http://dx.doi.org/10.1016/j.redox.2019.101226 |