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ERCC1/XPF Is Important for Repair of DNA Double-Strand Breaks Containing Secondary Structures

The structure-specific endonuclease ERCC1/XPF plays an important role in nucleotide excision repair and interstrand cross-link repair. In this study, we identified new functions of ERCC1/XPF in DNA double-strand break (DSB) repair. We found that the conserved function of ERCC1/XPF to remove non-homo...

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Detalles Bibliográficos
Autores principales: Li, Shibo, Lu, Hongyan, Wang, Zi, Hu, Qing, Wang, Hongjun, Xiang, Rong, Chiba, Takuya, Wu, Xiaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543133/
https://www.ncbi.nlm.nih.gov/pubmed/31153042
http://dx.doi.org/10.1016/j.isci.2019.05.017