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MiR-193a regulates chemoresistance of human osteosarcoma cells via repression of IRS2

Chemoresistance prevents curative potential of chemotherapy in most cases. MicroRNAs (miRNAs) are key players in regulating chemoresistance in osteosarcoma, which is the most common primary bone cancer. Bisulfite sequencing and quantitative real time PCR analyses showed that miR-193a expression is d...

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Detalles Bibliográficos
Autores principales: Wang, Haiyan, Zhao, Fangfang, Cai, Shanbao, Pu, Youguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543196/
https://www.ncbi.nlm.nih.gov/pubmed/31193934
http://dx.doi.org/10.1016/j.jbo.2019.100241