Dexmedetomidine reduces hippocampal microglia inflammatory response induced by surgical injury through inhibiting NLRP3

PURPOSE: To investigate whether dexmedetomidine (Dex) can reduce the production of inflammatory factor IL-1β by inhibiting the activation of NLRP3 inflammasome in hippocampal microglia, thereby alleviating the inflammatory response of the central nervous system induced by surgical injury. METHODS: E...

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Detalles Bibliográficos
Autores principales: Peng, Ji, Zhang, Peng, Zheng, Han, Ren, Yun-Qin, Yan, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543266/
https://www.ncbi.nlm.nih.gov/pubmed/31056470
http://dx.doi.org/10.1016/j.cjtee.2019.03.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543266/
https://www.ncbi.nlm.nih.gov/pubmed/31056470
http://dx.doi.org/10.1016/j.cjtee.2019.03.002

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