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Dexmedetomidine reduces hippocampal microglia inflammatory response induced by surgical injury through inhibiting NLRP3
PURPOSE: To investigate whether dexmedetomidine (Dex) can reduce the production of inflammatory factor IL-1β by inhibiting the activation of NLRP3 inflammasome in hippocampal microglia, thereby alleviating the inflammatory response of the central nervous system induced by surgical injury. METHODS: E...
Autores principales: | Peng, Ji, Zhang, Peng, Zheng, Han, Ren, Yun-Qin, Yan, Hong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543266/ https://www.ncbi.nlm.nih.gov/pubmed/31056470 http://dx.doi.org/10.1016/j.cjtee.2019.03.002 |
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