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Direct Inhibition of IRF-Dependent Transcriptional Regulatory Mechanisms Associated With Disease

Interferon regulatory factors (IRFs) are a family of homologous proteins that regulate the transcription of interferons (IFNs) and IFN-induced gene expression. As such they are important modulating proteins in the Toll-like receptor (TLR) and IFN signaling pathways, which are vital elements of the i...

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Detalles Bibliográficos
Autores principales: Antonczyk, Aleksandra, Krist, Bart, Sajek, Malgorzata, Michalska, Agata, Piaszyk-Borychowska, Anna, Plens-Galaska, Martyna, Wesoly, Joanna, Bluyssen, Hans A. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543449/
https://www.ncbi.nlm.nih.gov/pubmed/31178872
http://dx.doi.org/10.3389/fimmu.2019.01176