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Neuronal methylome reveals CREB-associated neuro-axonal impairment in multiple sclerosis
BACKGROUND: Due to limited access to brain tissue, the precise mechanisms underlying neuro-axonal dysfunction in neurological disorders such as multiple sclerosis (MS) are largely unknown. In that context, profiling DNA methylation, which is a stable and cell type-specific regulatory epigenetic mark...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543588/ https://www.ncbi.nlm.nih.gov/pubmed/31146783 http://dx.doi.org/10.1186/s13148-019-0678-1 |