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Optimization of an in vitro bilayer model for studying the functional interplay between human primary retinal pigment epithelial and choroidal endothelial cells isolated from donor eyes

OBJECTIVE: The microenvironment of outer retina is largely regulated by retinal pigment epithelium (RPE) and choroid. Damage to either of these layers lead to the development of age related macular degeneration (AMD). A simplified cell culture model that mimics the RPE/Bruch’s membrane (BM) and chor...

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Detalles Bibliográficos
Autores principales: Palanisamy, Karthikka, Karunakaran, Coral, Raman, Rajiv, Chidambaram, Subbulakshmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543644/
https://www.ncbi.nlm.nih.gov/pubmed/31146784
http://dx.doi.org/10.1186/s13104-019-4333-x