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Upregulation of NPL4 promotes bladder cancer cell proliferation by inhibiting DXO destabilization of cyclin D1 mRNA

BACKGROUND: NPL4 is an important cofactor of the valosin-containing protein (VCP)–NPL4–UFD1 complex. The VCP–NPL4–UFD1 has been considered as a ubiquitin proteasome system (UPS) regulator and response to protein degradation. While NPL4 plays important roles in various diseases, little is known about...

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Detalles Bibliográficos
Autores principales: Lu, Bao-Sai, Yin, Yue-Wei, Zhang, Yan-Ping, Guo, Ping-Ying, Li, Wei, Liu, Kai-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543671/
https://www.ncbi.nlm.nih.gov/pubmed/31164795
http://dx.doi.org/10.1186/s12935-019-0874-2