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Upregulation of NPL4 promotes bladder cancer cell proliferation by inhibiting DXO destabilization of cyclin D1 mRNA
BACKGROUND: NPL4 is an important cofactor of the valosin-containing protein (VCP)–NPL4–UFD1 complex. The VCP–NPL4–UFD1 has been considered as a ubiquitin proteasome system (UPS) regulator and response to protein degradation. While NPL4 plays important roles in various diseases, little is known about...
Autores principales: | Lu, Bao-Sai, Yin, Yue-Wei, Zhang, Yan-Ping, Guo, Ping-Ying, Li, Wei, Liu, Kai-Long |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543671/ https://www.ncbi.nlm.nih.gov/pubmed/31164795 http://dx.doi.org/10.1186/s12935-019-0874-2 |
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