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Role of Dsg1- and Dsg3-Mediated Signaling in Pemphigus Autoantibody-Induced Loss of Keratinocyte Cohesion

Pemphigus is an autoimmune dermatosis in which mucocutaneous blisters are induced primarily by autoantibodies against Desmoglein (Dsg) 1 and 3. Pemphigus vulgaris (PV) usually is associated with autoantibodies against Dsg3 whereas pemphigus foliaceus (PF) patients present autoantibodies against Dsg1...

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Detalles Bibliográficos
Autores principales: Walter, Elias, Vielmuth, Franziska, Wanuske, Marie-Therès, Seifert, Matthias, Pollmann, Robert, Eming, Rüdiger, Waschke, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543754/
https://www.ncbi.nlm.nih.gov/pubmed/31178865
http://dx.doi.org/10.3389/fimmu.2019.01128