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Use of Ceftriaxone in Treating Cognitive and Neuronal Deficits Associated With Dementia With Lewy Bodies

Dementia with Lewy bodies (DLB) is caused by accumulation of Lewy bodies, destruction of mitochondria, and excess of glutamate in synapses, which eventually leads to excitotoxicity, neurodegeneration, and cognitive impairments. Ceftriaxone (CEF) reduces excitotoxicity by increasing glutamate transpo...

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Detalles Bibliográficos
Autores principales: Ho, Ying-Jui, Shen, Mei-Shiuan, Tai, Chun-Hwei, Li, Hsin-Hua, Chen, Jian-Horng, Liao, Wen-Chieh, Chiu, Pai-Yi, Lee, I-Yen, Lin, Chih-Li, Hung, Ching-Sui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543807/
https://www.ncbi.nlm.nih.gov/pubmed/31178684
http://dx.doi.org/10.3389/fnins.2019.00507