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Use of Ceftriaxone in Treating Cognitive and Neuronal Deficits Associated With Dementia With Lewy Bodies
Dementia with Lewy bodies (DLB) is caused by accumulation of Lewy bodies, destruction of mitochondria, and excess of glutamate in synapses, which eventually leads to excitotoxicity, neurodegeneration, and cognitive impairments. Ceftriaxone (CEF) reduces excitotoxicity by increasing glutamate transpo...
Autores principales: | Ho, Ying-Jui, Shen, Mei-Shiuan, Tai, Chun-Hwei, Li, Hsin-Hua, Chen, Jian-Horng, Liao, Wen-Chieh, Chiu, Pai-Yi, Lee, I-Yen, Lin, Chih-Li, Hung, Ching-Sui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543807/ https://www.ncbi.nlm.nih.gov/pubmed/31178684 http://dx.doi.org/10.3389/fnins.2019.00507 |
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