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Macrophage Polarization: Different Gene Signatures in M1(LPS+) vs. Classically and M2(LPS–) vs. Alternatively Activated Macrophages

Macrophages are found in tissues, body cavities, and mucosal surfaces. Most tissue macrophages are seeded in the early embryo before definitive hematopoiesis is established. Others are derived from blood monocytes. The macrophage lineage diversification and plasticity are key aspects of their functi...

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Detalles Bibliográficos
Autores principales: Orecchioni, Marco, Ghosheh, Yanal, Pramod, Akula Bala, Ley, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543837/
https://www.ncbi.nlm.nih.gov/pubmed/31178859
http://dx.doi.org/10.3389/fimmu.2019.01084