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Pan-cancer repository of validated natural and cryptic mRNA splicing mutations

We present a major public resource of mRNA splicing mutations validated according to multiple lines of evidence of abnormal gene expression. Likely mutations present in all tumor types reported in the Cancer Genome Atlas (TCGA) and the International Cancer Genome Consortium (ICGC) were identified ba...

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Detalles Bibliográficos
Autores principales: Shirley, Ben C., Mucaki, Eliseos J., Rogan, Peter K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544075/
https://www.ncbi.nlm.nih.gov/pubmed/31275557
http://dx.doi.org/10.12688/f1000research.17204.3