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Developmental Apoptosis Promotes a Disease-Related Gene Signature and Independence from CSF1R Signaling in Retinal Microglia
Microglia have important remodeling functions in neurodevelopment, aging, and disease, with evidence for molecular diversity. However, the signaling pathways and environmental cues that drive diverse states of microglia are incompletely understood. We profiled microglia of a discrete developing CNS...
Autores principales: | Anderson, Sarah R., Roberts, Jacqueline M., Zhang, Jianmin, Steele, Michael R., Romero, Cesar O., Bosco, Alejandra, Vetter, Monica L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544177/ https://www.ncbi.nlm.nih.gov/pubmed/31091440 http://dx.doi.org/10.1016/j.celrep.2019.04.062 |
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