Epistasis detectably alters correlations between genomic sites in a narrow parameter window

Different genomic sites evolve inter-dependently due to the combined action of epistasis, defined as a non-multiplicative contribution of alleles at different loci to genome fitness, and the physical linkage of different loci in genome. Both epistasis and linkage, partially compensated by recombinat...

Descripción completa

Detalles Bibliográficos
Autores principales: Pedruzzi, Gabriele, Rouzine, Igor M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544209/
https://www.ncbi.nlm.nih.gov/pubmed/31150393
http://dx.doi.org/10.1371/journal.pone.0214036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544209/
https://www.ncbi.nlm.nih.gov/pubmed/31150393
http://dx.doi.org/10.1371/journal.pone.0214036

Ejemplares similares