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Epistasis detectably alters correlations between genomic sites in a narrow parameter window
Different genomic sites evolve inter-dependently due to the combined action of epistasis, defined as a non-multiplicative contribution of alleles at different loci to genome fitness, and the physical linkage of different loci in genome. Both epistasis and linkage, partially compensated by recombinat...
Autores principales: | Pedruzzi, Gabriele, Rouzine, Igor M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544209/ https://www.ncbi.nlm.nih.gov/pubmed/31150393 http://dx.doi.org/10.1371/journal.pone.0214036 |
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