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Low altitude simulation without hypoxia improves left ventricular function after myocardial infarction by reducing ventricular afterload

Humans have a lower risk of death from myocardial infarction (MI) living at low elevations (<2500 m), which are not high enough to induce hypoxia. Both chronic hypoxia pre-MI, achieved by altitude simulation >5000 m, and intermittent hypobaric hypoxia post-MI can reduce MI size in rodents, and...

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Detalles Bibliográficos
Autores principales: Shahid, Anmol, Patel, Vaibhav B., Morton, Jude S., Stenson, Trevor H., Davidge, Sandra T., Oudit, Gavin Y., McMurtry, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544215/
https://www.ncbi.nlm.nih.gov/pubmed/31150412
http://dx.doi.org/10.1371/journal.pone.0215814