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Pathogenicity of the H1N1 influenza virus enhanced by functional synergy between the NP(V100I) and NA(D248N) pair

By comparing and measuring covariations of viral protein sequences from isolates of the 2009 pH1N1 influenza A virus (IAV), specific substitutions that co-occur in the NP-NA pair were identified. To investigate the effect of these co-occurring substitution pairs, the V100I substitution in NP and the...

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Detalles Bibliográficos
Autores principales:	Kim, Woo-Jong, Hur, Kye-Yeon, Park, Han Wook, Lee, Seung-Woo, Yoo, Joo-Yeon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544299/ https://www.ncbi.nlm.nih.gov/pubmed/31150476 http://dx.doi.org/10.1371/journal.pone.0217691

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