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Chemical proteasome inhibition as a novel animal model of inner retinal degeneration in rats

Chemical proteasome inhibition has been a valuable animal model of neurodegeneration to uncover roles for the ubiquitin-proteasome system in the central nervous system. However, little is known about the effects of chemical proteasome inhibitors on retinal integrity. Therefore, we characterized the...

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Detalles Bibliográficos
Autores principales: Kageyama, Masaaki, Ota, Takashi, Sasaoka, Masaaki, Katsuta, Osamu, Shinomiya, Katsuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544319/
https://www.ncbi.nlm.nih.gov/pubmed/31150519
http://dx.doi.org/10.1371/journal.pone.0217945