Cargando…

Drug combination sensitivity scoring facilitates the discovery of synergistic and efficacious drug combinations in cancer

High-throughput drug screening has facilitated the discovery of drug combinations in cancer. Many existing studies adopted a full matrix design, aiming for the characterization of drug pair effects for cancer cells. However, the full matrix design may be suboptimal as it requires a drug pair to be c...

Descripción completa

Detalles Bibliográficos
Autores principales: Malyutina, Alina, Majumder, Muntasir Mamun, Wang, Wenyu, Pessia, Alberto, Heckman, Caroline A., Tang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544320/
https://www.ncbi.nlm.nih.gov/pubmed/31107860
http://dx.doi.org/10.1371/journal.pcbi.1006752