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Drug combination sensitivity scoring facilitates the discovery of synergistic and efficacious drug combinations in cancer
High-throughput drug screening has facilitated the discovery of drug combinations in cancer. Many existing studies adopted a full matrix design, aiming for the characterization of drug pair effects for cancer cells. However, the full matrix design may be suboptimal as it requires a drug pair to be c...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544320/ https://www.ncbi.nlm.nih.gov/pubmed/31107860 http://dx.doi.org/10.1371/journal.pcbi.1006752 |