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Development of chimeric and bifunctional antagonists for CLR/RAMP receptors

CGRP, adrenomedullin (ADM), and adrenomedullin 2 (ADM2) family peptides are important neuropeptides and hormones for the regulation of neurotransmission, vasotone, cardiovascular morphogenesis, vascular integrity, and feto‒placental development. These peptides signal through CLR/RAMP1, 2 and 3 recep...

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Detalles Bibliográficos
Autores principales: Chang, Chia Lin, Hsu, Sheau Yu Teddy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544337/
https://www.ncbi.nlm.nih.gov/pubmed/31150417
http://dx.doi.org/10.1371/journal.pone.0216996