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Multiple rare and common variants in APOB gene locus associated with oxidatively modified low-density lipoprotein levels

Oxidatively modified low-density lipoproteins (oxLDL) play an important role in the occurrence and progression of atherosclerosis. To identify the genetic factors influencing the oxLDL levels, we have genotyped 776 DNA samples of Russian individuals for 196,725 single-nucleotide polymorphisms (SNPs)...

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Detalles Bibliográficos
Autores principales: Khlebus, Eleonora, Kutsenko, Vladimir, Meshkov, Alexey, Ershova, Alexandra, Kiseleva, Anna, Shevtsov, Anton, Shcherbakova, Natalia, Zharikova, Anastasiia, Lankin, Vadim, Tikhaze, Alla, Chazova, Irina, Yarovaya, Elena, Drapkina, Oksana, Boytsov, Sergey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544350/
https://www.ncbi.nlm.nih.gov/pubmed/31150472
http://dx.doi.org/10.1371/journal.pone.0217620