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Diabetes downregulates renal adenosine A(2A) receptors in an experimental model of hypertension

Studies on diabetic nephropathy rarely take into account that the co-existence of diabetes and hypertension is frequent and further aggravates the prognosis of renal dysfunction. Adenosine can activate four subtypes of adenosine receptors (A(1), A(2A), A(2B) and A(3)) and has been implicated in diab...

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Detalles Bibliográficos
Autores principales: Patinha, Daniela, Carvalho, Carla, Abreu, Carla, Cunha, Olga M., Mota, Mariana C., Afonso, Joana, Albino-Teixeira, António, Diniz, Carmen, Morato, Manuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544351/
https://www.ncbi.nlm.nih.gov/pubmed/31150459
http://dx.doi.org/10.1371/journal.pone.0217552