Cargando…

Interleukin 1 is a key driver of inflammatory bowel disease-demonstration in a murine IL-1Ra knockout model

Interleukin 1 (IL-1) is an important mediator of inflammation and tissue damage in inflammatory bowel disease (IBD). The balance between IL-1 and IL-1Ra as a natural inhibitor plays a vital role in a variety of diseases. Here, we investigated whether changes seen during IBD are induced spontaneously...

Descripción completa

Detalles Bibliográficos
Autores principales: Dosh, Rasha H., Jordan-Mahy, Nicola, Sammon, Christopher, Le Maitre, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544399/
https://www.ncbi.nlm.nih.gov/pubmed/31191826
http://dx.doi.org/10.18632/oncotarget.26894