Identification of EOMES-expressing spermatogonial stem cells and their regulation by PLZF

Long-term maintenance of spermatogenesis in mammals is supported by GDNF, an essential growth factor required for spermatogonial stem cell (SSC) self-renewal. Exploiting a transgenic GDNF overexpression model, which expands and normalizes the pool of undifferentiated spermatogonia between Plzf (+/+)...

Descripción completa

Detalles Bibliográficos
Autores principales: Sharma, Manju, Srivastava, Anuj, Fairfield, Heather E, Bergstrom, David, Flynn, William F, Braun, Robert E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544432/
https://www.ncbi.nlm.nih.gov/pubmed/31149899
http://dx.doi.org/10.7554/eLife.43352

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544432/
https://www.ncbi.nlm.nih.gov/pubmed/31149899
http://dx.doi.org/10.7554/eLife.43352

Ejemplares similares