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Identification of EOMES-expressing spermatogonial stem cells and their regulation by PLZF

Long-term maintenance of spermatogenesis in mammals is supported by GDNF, an essential growth factor required for spermatogonial stem cell (SSC) self-renewal. Exploiting a transgenic GDNF overexpression model, which expands and normalizes the pool of undifferentiated spermatogonia between Plzf (+/+)...

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Detalles Bibliográficos
Autores principales:	Sharma, Manju, Srivastava, Anuj, Fairfield, Heather E, Bergstrom, David, Flynn, William F, Braun, Robert E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2019
Materias:	Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544432/ https://www.ncbi.nlm.nih.gov/pubmed/31149899 http://dx.doi.org/10.7554/eLife.43352

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