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Functional evaluation of transposable elements as enhancers in mouse embryonic and trophoblast stem cells

Transposable elements (TEs) are thought to have helped establish gene regulatory networks. Both the embryonic and extraembryonic lineages of the early mouse embryo have seemingly co-opted TEs as enhancers, but there is little evidence that they play significant roles in gene regulation. Here we test...

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Detalles Bibliográficos
Autores principales: Todd, Christopher D, Deniz, Özgen, Taylor, Darren, Branco, Miguel R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544436/
https://www.ncbi.nlm.nih.gov/pubmed/31012843
http://dx.doi.org/10.7554/eLife.44344