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Symmetry transitions during gating of the TRPV2 ion channel in lipid membranes

The Transient Receptor Potential Vanilloid 2 (TRPV2) channel is a member of the temperature-sensing thermoTRPV family. Recent advances in cryo-electronmicroscopy (cryo-EM) and X-ray crystallography have provided many important insights into the gating mechanisms of thermoTRPV channels. Interestingly...

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Detalles Bibliográficos
Autores principales: Zubcevic, Lejla, Hsu, Allen L, Borgnia, Mario J, Lee, Seok-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544438/
https://www.ncbi.nlm.nih.gov/pubmed/31090543
http://dx.doi.org/10.7554/eLife.45779