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Altered human oligodendrocyte heterogeneity in multiple sclerosis

Oligodendrocyte (OL) pathology is increasingly implicated in neurodegenerative diseases as OLs both myelinate and provide metabolic support to axons. In Multiple Sclerosis (MS), demyelination in the central nervous system (CNS) thus leads to neurodegeneration, but the severity of MS between patients...

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Detalles Bibliográficos
Autores principales: Jäkel, Sarah, Agirre, Eneritz, Falcão, Ana Mendanha, van Bruggen, David, Lee, Ka Wai, Knuesel, Irene, Malhotra, Dheeraj, ffrench-Constant, Charles, Williams, Anna, Castelo-Branco, Gonçalo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544546/
https://www.ncbi.nlm.nih.gov/pubmed/30747918
http://dx.doi.org/10.1038/s41586-019-0903-2