Towards a Generic Tool for Prediction of Meropenem Systemic and Infection-Site Exposure: A Physiologically Based Pharmacokinetic Model for Adult Patients with Pneumonia

OBJECTIVE: The objective of this study was to develop a physiologically based pharmacokinetic model for meropenem using a retrograde approach, which could serve as a basis for prediction of the systemic and infection-site drug exposures in different populations and indications. We intended this mode...

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Detalles Bibliográficos
Autores principales: Thémans, Pauline, Marquet, Pierre, Winkin, Joseph J., Musuamba, Flora T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544603/
https://www.ncbi.nlm.nih.gov/pubmed/31090024
http://dx.doi.org/10.1007/s40268-019-0268-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544603/
https://www.ncbi.nlm.nih.gov/pubmed/31090024
http://dx.doi.org/10.1007/s40268-019-0268-x

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