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Periodontal treatment prevents arthritis in mice and methotrexate ameliorates periodontal bone loss
Recent studies indicate a causal relationship between the periodontal pathogen P. gingivalis and rheumatoid arthritis involving the production of autoantibodies against citrullinated peptides. We therefore postulated that therapeutic eradication P. gingivalis may ameliorate rheumatoid arthritis deve...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544621/ https://www.ncbi.nlm.nih.gov/pubmed/31148565 http://dx.doi.org/10.1038/s41598-019-44512-9 |