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Periodontal treatment prevents arthritis in mice and methotrexate ameliorates periodontal bone loss

Recent studies indicate a causal relationship between the periodontal pathogen P. gingivalis and rheumatoid arthritis involving the production of autoantibodies against citrullinated peptides. We therefore postulated that therapeutic eradication P. gingivalis may ameliorate rheumatoid arthritis deve...

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Detalles Bibliográficos
Autores principales: Lübcke, Paul M., Ebbers, Meinolf N. B., Volzke, Johann, Bull, Jana, Kneitz, Susanne, Engelmann, Robby, Lang, Hermann, Kreikemeyer, Bernd, Müller-Hilke, Brigitte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544621/
https://www.ncbi.nlm.nih.gov/pubmed/31148565
http://dx.doi.org/10.1038/s41598-019-44512-9