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N-acetylcysteine prevents bladder tissue fibrosis in a lipopolysaccharide-induced cystitis rat model

Therapeutic options for non-Hunner type interstitial cystitis (IC), which is histologically characterized by fibrosis and mast cell infiltration, are limited. We developed a rat model that replicates chronic inflammation and fibrosis and evaluated the therapeutic effect of N-acetylcysteine (NAC), a...

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Detalles Bibliográficos
Autores principales: Ryu, Chae-Min, Shin, Jung Hyun, Yu, Hwan Yeul, Ju, Hyein, Kim, Sujin, Lim, Jisun, Heo, Jinbeom, Lee, Seungun, Shin, Dong-Myung, Choo, Myung-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544636/
https://www.ncbi.nlm.nih.gov/pubmed/31148586
http://dx.doi.org/10.1038/s41598-019-44631-3