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Differential binding cell-SELEX method to identify cell-specific aptamers using high-throughput sequencing

Aptamers have in recent years emerged as a viable alternative to antibodies. High-throughput sequencing (HTS) has revolutionized aptamer research by increasing the number of reads from a few (using Sanger sequencing) to millions (using an HTS approach). Despite the availability and advantages of HTS...

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Detalles Bibliográficos
Autores principales: Pleiko, Karlis, Saulite, Liga, Parfejevs, Vadims, Miculis, Karlis, Vjaters, Egils, Riekstina, Una
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544647/
https://www.ncbi.nlm.nih.gov/pubmed/31148584
http://dx.doi.org/10.1038/s41598-019-44654-w