Leveraging heterogeneous data from GHS toxicity annotations, molecular and protein target descriptors and Tox21 assay readouts to predict and rationalise acute toxicity

Despite the increasing knowledge in both the chemical and biological domains the assimilation and exploration of heterogeneous datasets, encoding information about the chemical, bioactivity and phenotypic properties of compounds, remains a challenge due to requirement for overlap between chemicals a...

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Detalles Bibliográficos
Autores principales: Allen, Chad H. G., Mervin, Lewis H., Mahmoud, Samar Y., Bender, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544914/
https://www.ncbi.nlm.nih.gov/pubmed/31152262
http://dx.doi.org/10.1186/s13321-019-0356-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544914/
https://www.ncbi.nlm.nih.gov/pubmed/31152262
http://dx.doi.org/10.1186/s13321-019-0356-5

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