Genome-wide DNA methylation and hydroxymethylation analysis reveal human menstrual blood-derived stem cells inhibit hepatocellular carcinoma growth through oncogenic pathway suppression via regulating 5-hmC in enhancer elements

BACKGROUND: Epigenetic alteration is an important indicator of crosstalk between cancer cells and surrounding microenvironment components including mesenchymal stem cells (MSC). Human menstrual blood-derived stem cells (MenSCs) are novel source of MSCs which exert suppressive effects on cancers via...

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Detalles Bibliográficos
Autores principales: Wu, Yichen, Chen, Xin, Zhao, Yongjia, Wang, Yanling, Li, Yifei, Xiang, Charlie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544940/
https://www.ncbi.nlm.nih.gov/pubmed/31151404
http://dx.doi.org/10.1186/s13287-019-1243-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544940/
https://www.ncbi.nlm.nih.gov/pubmed/31151404
http://dx.doi.org/10.1186/s13287-019-1243-8

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