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Genome-wide DNA methylation and hydroxymethylation analysis reveal human menstrual blood-derived stem cells inhibit hepatocellular carcinoma growth through oncogenic pathway suppression via regulating 5-hmC in enhancer elements
BACKGROUND: Epigenetic alteration is an important indicator of crosstalk between cancer cells and surrounding microenvironment components including mesenchymal stem cells (MSC). Human menstrual blood-derived stem cells (MenSCs) are novel source of MSCs which exert suppressive effects on cancers via...
Autores principales: | Wu, Yichen, Chen, Xin, Zhao, Yongjia, Wang, Yanling, Li, Yifei, Xiang, Charlie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544940/ https://www.ncbi.nlm.nih.gov/pubmed/31151404 http://dx.doi.org/10.1186/s13287-019-1243-8 |
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