Alpha-mangostin induces endoplasmic reticulum stress and autophagy which count against fatty acid synthase inhibition mediated apoptosis in human breast cancer cells

BACKGROUND/AIMS: One of the most important metabolic hallmarks of breast cancer cells is enhanced lipogenesis. Increasing evidences suggest that fatty acid synthase (FAS) plays an important role in human breast cancer. Previously we discovered that alpha-mangostin showed apoptotic effect on human br...

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Detalles Bibliográficos
Autores principales: Huang, Wenyuan, Liang, Yan, Ma, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544980/
https://www.ncbi.nlm.nih.gov/pubmed/31164796
http://dx.doi.org/10.1186/s12935-019-0869-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544980/
https://www.ncbi.nlm.nih.gov/pubmed/31164796
http://dx.doi.org/10.1186/s12935-019-0869-z

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