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Alpha-mangostin induces endoplasmic reticulum stress and autophagy which count against fatty acid synthase inhibition mediated apoptosis in human breast cancer cells
BACKGROUND/AIMS: One of the most important metabolic hallmarks of breast cancer cells is enhanced lipogenesis. Increasing evidences suggest that fatty acid synthase (FAS) plays an important role in human breast cancer. Previously we discovered that alpha-mangostin showed apoptotic effect on human br...
Autores principales: | Huang, Wenyuan, Liang, Yan, Ma, Xiaofeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544980/ https://www.ncbi.nlm.nih.gov/pubmed/31164796 http://dx.doi.org/10.1186/s12935-019-0869-z |
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