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Widespread selection for extremely high and low levels of secondary structure in coding sequences across all domains of life

Codon composition, GC content and local RNA secondary structures can have a profound effect on gene expression, and mutations affecting these parameters, even though they do not alter the protein sequence, are not neutral in terms of selection. Although evidence exists that, in some cases, selection...

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Detalles Bibliográficos
Autores principales: Gebert, Daniel, Jehn, Julia, Rosenkranz, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544989/
https://www.ncbi.nlm.nih.gov/pubmed/31138098
http://dx.doi.org/10.1098/rsob.190020