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Widespread selection for extremely high and low levels of secondary structure in coding sequences across all domains of life
Codon composition, GC content and local RNA secondary structures can have a profound effect on gene expression, and mutations affecting these parameters, even though they do not alter the protein sequence, are not neutral in terms of selection. Although evidence exists that, in some cases, selection...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544989/ https://www.ncbi.nlm.nih.gov/pubmed/31138098 http://dx.doi.org/10.1098/rsob.190020 |