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Feasibility of repairing full-thickness skin defects by iPSC-derived epithelial stem cells seeded on a human acellular amniotic membrane

BACKGROUND: Induced pluripotent stem cells (iPSCs) can generate epithelial stem cells (EpSCs) as seed cells for skin substitutes to repair skin defects. Here, we investigated the effects of a human acellular amniotic membrane (hAAM) combined with iPSC-derived CD200(+)/ITGA6(+) EpSCs as a skin substi...

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Detalles Bibliográficos
Autores principales: Zhou, Huateng, Wang, Lixiang, Zhang, Cui, Hu, Jintao, Chen, Jianlin, Du, Weibin, Liu, Fei, Ren, Weifan, Wang, Jinfu, Quan, Renfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545005/
https://www.ncbi.nlm.nih.gov/pubmed/31151466
http://dx.doi.org/10.1186/s13287-019-1234-9